Advanced glycation end products (AGEs) are a complex group of compounds formed when sugar reacts with amino acids.
This can occur both in the food you eat, and inside your body.
It’s is a fitting acronym because – along with oxidation – it’s one of the major molecular mechanisms whereby damage accrues in your body, which leads to disease, aging, and eventually, death.
For example, there is mounting evidence that AGEs may be implicated in the development of the chronic degenerative diseases associated with aging, including but not limited to:
- Cardiovascular disease
- Alzheimer’s disease, and
Several studies have shown that restricting the consumption of AGEs can lead to an increased lifespan in animal models.
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